e., numerous copies on the gene for cytochrome P450 isoenzyme 2D6 or substantial morphine concentrations). Kids with rest apnea can be specifically sensitive towards the respiratory depressant consequences of codeine. As a result of possibility of everyday living-threatening respiratory despair and death:
Accidental ingestion of acetaminophen and codeine phosphate tablets, Particularly by children, may lead to respiratory depression and death because of an overdose of codeine.
Lifestyle-Threatening Respiratory Depression Inform sufferers of the chance of existence-threatening respiratory melancholy, like information and facts that the risk is biggest when starting acetaminophen and codeine phosphate tablets or if the dosage is enhanced, Which it might happen even at suggested dosages.
No, it can be under no circumstances encouraged to choose Alcoholic beverages with Valium 10mg Tablet because it might cause respiratory challenges, sleepiness and coronary heart complications. Having Valium 10mg Tablet with alcohol may possibly make you sleepy as well as your respiration could develop into so shallow that you may not wake up. This will even bring about Demise.
Critical Information Guiding Use in Pediatric Individuals: Do not give acetaminophen and codeine phosphate tablets to a youngster younger than twelve a long time of age. Do not give acetaminophen and codeine phosphate tablets to a child more youthful than 18 several years of age soon after operation to eliminate the tonsils and/or adenoids.
The concomitant utilization of acetaminophen and codeine phosphate tablets with all cytochrome P450 2D6 inhibitors (e.g., amiodarone, quinidine) may perhaps result in a rise in codeine plasma concentrations and also a lower in Lively metabolite morphine plasma focus which could end in an analgesic efficacy reduction or symptoms of opioid withdrawal.
are afflicted with bronchitis (an inflammation on the lining in the tubes during the lungs, leading to coughing spells accompanied by thick phlegm and breathlessness) or emphysema (a lung situation which leaves you struggling for breath)
The safety and effectiveness of acetaminophen and codeine phosphate tablets in pediatric people underneath the age of 18 haven't been founded.
Interactions with Benzodiazepines as well as other CNS Depressants Notify clients and caregivers that perhaps fatal additive effects may perhaps take place if acetaminophen and codeine phosphate tablets are used with benzodiazepines or other CNS depressants, which include alcohol, rather than to use these medicine concomitantly Unless of course supervised by a Health care supplier (see WARNINGS and Safety measures, Drug Interactions).
Look at prescribing naloxone in the event the read more individual has residence customers (including children) or other close contacts at risk for accidental ingestion or overdose.
have ever had a reaction to or been instructed that you'll be allergic to codeine phosphate, almost every other opioid analgesic or any of another elements in the tablets (see portion 6)
The analgesic Qualities of codeine happen to be speculated to originate from its conversion to morphine, Even though the exact mechanism of analgesic action remains unidentified.
Patients at substantial possibility of acetaminophen and codeine phosphate tablets abuse include These having a record of extended usage of any opioid, together with products and solutions made up of codeine, Those people by using a historical past of drug or Alcoholic beverages abuse, or people that use acetaminophen and codeine phosphate tablets together with other abused prescription drugs.
Resulting from inconsistencies in between the drug labels on DailyMed and the tablet photographs provided by RxImage, we now not Screen the RxImage tablet pictures linked to drug labels.